The 10th IAS Conference on HIV Science (IAS 2019) welcomes the submission of abstracts in the following scientific tracks:
- Track A: Basic Science
- Track B: Clinical Science
- Track C: Prevention Science
- Track D: Social, behavioural and implementation science
Abstract submissions will open on 1 December 2018. For detailed descriptions of each scientific track, please see the track scope and objectives and abstract categories below. Full submission guidelines are available here.
Track scope and objectives
The scientific track is the general heading under which your abstract, if accepted, will be reviewed and later published in the conference printed matters. Please choose the scientific track that best describes the subject of your abstract.
Track A: Basic Science
Track A will focus on recent advancements made through both basic and translational research to further our understanding of HIV replication, transmission, pathogenesis and persistence. Highlights will include advances in:
- Molecular virology (HIV replication and transmission)
- Vaccine development (both prophylactic and therapeutic)
- Biological variables in HIV pathogenesis and the implications on aging
- Persistent HIV infection
- Cure strategies.
We anticipate an emphasis on HIV persistence and novel curative strategies stemming from the identification of recently discovered clinically relevant reservoir sources and novel mechanisms driving persistence and latency. The track also encompasses T and B cell vaccinology by exploring the interplay between innate, humoral and cellular HIV immunity, as well as the role of NK cells in the control of HIV infection. Track A will also cover the molecular aspects of HIV infection, including the development of new antivirals to improve efficacy and durability for long-term treatment, and will explore the consequences of aging with HIV infection at the molecular level. In addition, it will explore the impact of gender, ethnicity and co-infections on HIV pathogenesis, persistence and curative strategies. Track A also highlights the development of novel technologies to advance basic HIV research, including single cell analysis, metabolomics and new animal models in HIV pathogenesis and cure studies.
Download the full list of track A abstract submission categories
Track B: Clinical Science
Track B will focus on the latest evidence, state of the art and challenges related to antiretroviral treatment in adults, children and key populations (women and transgender women) and in challenging socio-economic contexts. In addition to the intrinsic efficacy and safety of new regimens and strategies, it will incorporate the role that health systems play in the attainability of the UNAIDS 90-90-90 goals, bridging with Track D (Social, Behavioural and Implementation Science).
Track B will also bridge with Track C (Prevention) in the role of antiretrovirals for the prevention of HIV acquisition (PEP and PrEP). Track B will address the latest research in epidemiology, prevention and treatment of opportunistic infections; there will be special focus on tuberculosis as this infection continues to be the most significant opportunistic infection for people living with HIV worldwide. In this context, novel approaches to models of care of HIV/TB co-infection, as well as novel therapies, will be discussed. Other important opportunistic infections, such as cryptococcosis and histoplasmosis, will be addressed in terms of epidemiology, diagnostics and therapeutic interventions.
Track B will also focus on the clinical management of people living with HIV beyond antiretroviral treatment, especially in lower and middle-income countries (LMICs), including management of chronic non-AIDS-defining events and other non-communicable diseases, such as diabetes, cardiovascular disease and cancer and conditions relevant to aging populations. Finally, Track B will deal with care of PLHIV in the setting of complex humanitarian emergencies, such as earthquakes, flooding and war.
Download the full list of track B abstract submission categories
Track C: Prevention Science
Track C will focus on major advances in HIV prevention science, including progress in the development of primary prevention methods, challenges and successes in expanding access to effective HIV prevention, particularly for those at greatest need, and the impact of scaling up prevention on the HIV epidemic. Updates on the design and evaluation of next-generation primary prevention strategies, including long-acting and intermittent PrEP, broadly neutralizing antibodies and HIV vaccines, will be presented. The Prevention Science track will also discuss progress on novel approaches to monitoring of prevention programmes, as well as mathematical modelling outputs on the impact of PrEP across countries.
There will be a focus on advances at the intersections of HIV prevention and sexual and reproductive health, including inclusion of pregnant and breastfeeding women in HIV prevention trials, interactions between prevention products and exogenous hormones, and implications for STI control.
Track C will also specifically address key populations: drug users, poor and marginalized populations (such as homeless migrants and refugees), men who have sex with men and transgender women (especially those in LMICs where they face stigma and criminalization), sex workers and young women. The focus will be on combination interventions or programmes that address social and structural vulnerabilities to HIV in these particular populations, which may also be barriers to uptake and adherence to prevention interventions. In this way, the Prevention Science track in 2019 will focus both on iterations of a single intervention and combinations of different interventions.
Areas of special interest include:
- New ARVs for prevention
- Designing and implementing next-generation HIV prevention trials
- Immunization approaches: clinical trials on broadly neutralizing antibody and HIV and TB vaccines
- Treatment as prevention (TaSP) and U=U
- New prevention interventions for drug users, men who have sex with men and adolescents
- Combination/integrated prevention approaches
- Intersections with sexual and reproductive health, such as STI prevention interventions
- Novel monitoring and evaluation approaches
- HIV testing strategies for key populations, including self-testing
- Transgender populations
- Sex workers.
Download the full list of track C abstract submission categories
Track D: Social, Behavioural and Implementation Science
Evidence exists that ending the AIDS epidemic is possible with the use of a combination of strategies, including biomedical (PrEP, PEP and TaSP) and socio-behavioural prevention interventions, test-and-treat approaches and differentiated delivery of treatment and care. However, the translation of new evidence into policy and practice remains slow, undermining the ability to scale up effective prevention, treatment and care as rapidly as would be required to reach global targets. Track D will offer a critical analysis of the factors that hinder or enhance uptake, with a particular emphasis on emerging strategies, such as e-health, community-participatory models of service delivery, strengthening of health systems and policy development, as tools to accelerate the discovery-policy-implementation trajectory. It will also offer an analysis of economic and political factors that impact on service delivery at scale. New evidence in specific areas will be presented.
Presentations in the area of the first 90 in the 90-90-90 targets will cover effective strategies to improve diagnoses, including partner notification, self-testing, integrating testing with care for TB and other services.
Regarding community-level prevention and care, studies such as SEARCH will provide evidence for delivery of HIV test-and-treat approaches in real-life settings. This will also show how community-based HIV service delivery may impact broader health-related and economic/education outcomes.
The track will examine new and promising methodology. This will include:
- Using modelling to inform combination HIV prevention strategies and track incidence
- Implementation study approaches that better identify real-life challenges that impact trial results
- Better definitions and measurements for “epidemic control” and their application in real-world settings in view of currently available data
- Big data in surveillance and outcome measurement.
Finally, Track D will focus on implementation and scale up of HIV PrEP in real-life settings. This includes:
- Studying the effect of introducing PrEP into HIV prevention programmes, including addressing issues of health infrastructure, coverage, human resources, demand creation, community engagement and end-user support
- Looking at the political economy of HIV, such as new data on funding scenarios in countries that transition from reliance on international donor funding to domestic funding
- Assessing the impact of political crises on HIV service delivery
- Financially analysing differentiated prevention and care services.
Download the full list of track D abstract submission categories